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Descriptor English: Heterogeneous Nuclear Ribonucleoprotein D0
Descriptor Spanish: Ribonucleoproteína Nuclear Heterogénea D0
Descriptor ribonucleoproteína nuclear heterogénea D0
Entry term(s) proteína AUF1
proteína AUF1A
proteína de unión al ARN con elementos ricos en AU de tipo 1 de 37 kDa
proteína p37AUF1
Scope note: Miembro de una subfamilia de ribonucleoproteínas nucleares heterogéneas de expresión ubicua (hnRNPs), la ribonucleoproteína nuclear heterogénea D0 (hnRNP D0) se une específicamente a moléculas de ARN que contienen ELEMENTOS RICOS EN AU presentes en la región 3'-UTR del ARNm de muchos PROTOONCOGENES y CITOCINAS. Actúa como factor de transcripción; se une a secuencias de ADN bicatenario y monocatenario de manera específica.
Descriptor Portuguese: Ribonucleoproteína Nuclear Heterogênea D0
Descriptor French: Ribonucléoprotéine nucléaire hétérogène D0
Entry term(s): AU rich Element RNA binding Protein 1, 37 kDa
AU-rich Element RNA-binding Protein 1, 37 kDa
AUF1 Protein
AUF1 Protein, P37
AUF1A Protein
P37 AUF1 Protein
hnRNP D0
Tree number(s): D12.776.157.725.500.313.300.500
D12.776.157.725.813.750.300.500
D12.776.664.962.500.313.300.500
D12.776.664.962.813.750.300.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000081035
Scope note: Member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) specifically binds RNA molecules that contain AU RICH ELEMENTS found within the 3'-UTR of many PROTO-ONCOGENES and CYTOKINES mRNAs. It functions as a transcription factor, binds to double- and single-stranded DNA sequences in a specific manner.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2020; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 was indexed under RIBONUCLEOPROTEIN COMPLEX BINDING PROTEINS 1993-2002, under HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN D 2001-2019
History Note: 2020 (2001)
DeCS ID: 59120
Unique ID: D000081035
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/08/05
Heterogeneous Nuclear Ribonucleoprotein D0 - Preferred
Concept UI M0224484
Scope note Member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) specifically binds RNA molecules that contain AU RICH ELEMENTS found within the 3'-UTR of many PROTO-ONCOGENES and CYTOKINES mRNAs. It functions as a transcription factor, binds to double- and single-stranded DNA sequences in a specific manner.
Preferred term Heterogeneous Nuclear Ribonucleoprotein D0
Entry term(s) AU rich Element RNA binding Protein 1, 37 kDa
AU-rich Element RNA-binding Protein 1, 37 kDa
AUF1 Protein
AUF1 Protein, P37
AUF1A Protein
P37 AUF1 Protein
hnRNP D0



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