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Descriptor English: Promyelocytic Leukemia Nuclear Bodies
Descriptor Spanish: Cuerpos Nucleares de la Leucemia Promielocítica
Descriptor cuerpos nucleares de la leucemia promielocítica
Entry term(s) CN de la LMP
cuerpo nuclear de la leucemia promielocítica
cuerpo proteínico de la leucemia promielocítica
cuerpos de la LPM
cuerpos nucleares de la LPM
cuerpos proteínicos de la leucemia promielocítica
Scope note: Cuerpos esféricos intranucleares sin membrana nucleados por la PROTEÍNA DE LA LEUCEMIA PROMIELOCÍTICA y diversas otras proteínas que contienen un motivo de interacción de modificador pequeño relacionado con la ubiquitina (SUMO, por sus siglas en inglés), o SIM (por sus siglas en inglés), y/o proteínas sumoiladas (por ejemplo, proteína Sp100). Los cuerpos nucleares de la leucemia promielocítica regulan las modificaciones postraduccionales de las proteínas asociadas (por ejemplo, SUMOILACIÓN), que a su vez conducen a la modulación de diversos procesos biológicos.
Descriptor Portuguese: Corpos Nucleares da Leucemia Promielocítica
Descriptor French: Corps nucléaires de la leucémie promyélocytaire
Entry term(s): Nuclear Bodies, PML
Nuclear Body, PML
PML Bodies
PML Body
PML NBs
PML Nuclear Bodies
PML Nuclear Body
Promyelocytic Leukemia Nuclear Body
Promyelocytic Leukemia Protein Bodies
Promyelocytic Leukemia Protein Body
Tree number(s): A11.284.430.106.279.345.574.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000088182
Scope note: Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Intranuclear Inclusion Bodies (2008-2021)
Promyelocytic Leukemia Protein (2008-2021)
Public MeSH Note: 2022
History Note: 2022
DeCS ID: 59668
Unique ID: D000088182
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/01
Promyelocytic Leukemia Nuclear Bodies - Preferred
Concept UI M000740236
Scope note Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.
Preferred term Promyelocytic Leukemia Nuclear Bodies
Entry term(s) Nuclear Bodies, PML
Nuclear Body, PML
PML Bodies
PML Body
PML NBs
PML Nuclear Bodies
PML Nuclear Body
Promyelocytic Leukemia Nuclear Body
Promyelocytic Leukemia Protein Bodies
Promyelocytic Leukemia Protein Body



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