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Descriptor English: Designed Ankyrin Repeat Proteins
Descriptor Spanish: Proteínas de Repetición de Anquirina Diseñadas
Descriptor proteínas con repeticiones de anquirina diseñadas
Entry term(s) DARPina
DARPinas
Scope note: Proteínas miméticas de anticuerpos diseñadas genéticamente, derivadas de proteínas ANQUIRINAS. Ofrecen ventajas sobre los anticuerpos debido a su UNIÓN PROTEICA diana altamente específica con una afinidad y una especificidad elevadas.
Descriptor Portuguese: Proteínas de Repetição de Anquirina Projetadas
Descriptor French: Protéines conçues par répétition de motifs ankyrine
Entry term(s): DARPin
DARPins
Tree number(s): D12.776.828.150
J01.637.087.375
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090922
Scope note: Genetically engineered antibody MIMETIC PROTEINS, derived from ANKYRIN PROTEINS. They offer advantages over antibodies because of their highly specific target PROTEIN BINDING with high affinity and specificity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Ankyrin Repeat (2001-2021)
Public MeSH Note: 2022
History Note: 2022
DeCS ID: 59825
Unique ID: D000090922
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/28
Designed Ankyrin Repeat Proteins - Preferred
Concept UI M000747547
Scope note Genetically engineered antibody MIMETIC PROTEINS, derived from ANKYRIN PROTEINS. They offer advantages over antibodies because of their highly specific target PROTEIN BINDING with high affinity and specificity.
Preferred term Designed Ankyrin Repeat Proteins
Entry term(s) DARPin
DARPins



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