| Descriptor English: | Protein Glutamine gamma Glutamyltransferase 2 | ||||||
| Descriptor Spanish: |
Proteína Glutamina Gamma Glutamiltransferasa 2
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| Descriptor Portuguese: | Proteína 2 Glutamina gama-Glutamiltransferase | ||||||
| Descriptor French: | Protein glutamine gamma glutamyltransferase-2 | ||||||
| Entry term(s): |
Proteins, TGM2 TGM2 Proteins TGase II Tissue Transglutaminase Tissue Type Transglutaminase Tissue-Type Transglutaminase Transglutaminase 2 Transglutaminase C Transglutaminase II Transglutaminase, Tissue Transglutaminase, Tissue-Type |
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| Tree number(s): |
D08.811.913.050.200.800.650 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000091345 | ||||||
| Scope note: | Calcium-dependent acyltransferase that catalyzes cross-linking of proteins at a GLUTAMINE in one chain with primary amine such as in LYSINE in another chain. In addition it can also accept monoamine substrates to catalyze post-translational modifications (e.g., protein serotonylation). |
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| Annotation: | distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE which is involved with glutathione metabolism |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.3.2.13 | ||||||
| Public MeSH Note: | 2022; see under TRANSGLUTAMINASESE 1999-2021 |
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| History Note: | 2022(1999) |
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| DeCS ID: | 59866 | ||||||
| Unique ID: | D000091345 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2022/01/01 | ||||||
| Date of Entry: | 2021/07/09 | ||||||
| Revision Date: | 2021/07/01 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Protein Glutamine gamma Glutamyltransferase 2
- Preferred
| Concept UI |
M000748605 |
| Scope note | Calcium-dependent acyltransferase that catalyzes cross-linking of proteins at a GLUTAMINE in one chain with primary amine such as in LYSINE in another chain. In addition it can also accept monoamine substrates to catalyze post-translational modifications (e.g., protein serotonylation). |
| Preferred term | Protein Glutamine gamma Glutamyltransferase 2 |
| Entry term(s) |
Proteins, TGM2 TGM2 Proteins TGase II Tissue Transglutaminase Tissue Type Transglutaminase Tissue-Type Transglutaminase Transglutaminase 2 Transglutaminase C Transglutaminase II Transglutaminase, Tissue Transglutaminase, Tissue-Type |
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