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Descriptor English: First Generation Cephalosporins
Descriptor Spanish: Cefalosporinas de Primera Generación
Descriptor cefalosporinas de primera generación
Entry term(s) cefalosporina de primera generación
Scope note: CEFALOSPORINAS con excelente cobertura contra cocos grampositivos, como STAPHYLOCOCCUS y STREPTOCOCCUS. Tienen cierta actividad contra las bacterias gramnegativas, pero, en general, la actividad contra estas es menor que la de las cefalosporinas de segunda, tercera y cuarta generación.
Descriptor Portuguese: Cefalosporinas de Primeira Geração
Descriptor French: Without translation
Entry term(s): Cephalosporin, First Generation
Cephalosporins, First Generation
First Generation Cephalosporin
Generation Cephalosporin, First
Tree number(s): D27.505.954.122.085.386.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097904
Scope note: CEPHALOSPORIN agents with excellent coverage against gram-positive cocci, such as STAPHYLOCOCCUS and STREPTOCOCCUS. They have some activity against the gram-negative bacteria, but in general, gram-negative activity is decreased compared to 2nd, 3rd, and 4th generation cephalosporins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Cephalosporins (1981-2023)
Public MeSH Note: 2024
History Note: 2024
DeCS ID: 60695
Unique ID: D000097904
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/07/06
First Generation Cephalosporins - Preferred
Concept UI M000764689
Scope note CEPHALOSPORIN agents with excellent coverage against gram-positive cocci, such as STAPHYLOCOCCUS and STREPTOCOCCUS. They have some activity against the gram-negative bacteria, but in general, gram-negative activity is decreased compared to 2nd, 3rd, and 4th generation cephalosporins.
Preferred term First Generation Cephalosporins
Entry term(s) Cephalosporin, First Generation
Cephalosporins, First Generation
First Generation Cephalosporin
Generation Cephalosporin, First



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