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Descriptor English: Amoxapine
Descriptor Spanish: Amoxapina
Descriptor Portuguese: Amoxapina
Descriptor French: Amoxapine
Entry term(s): 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Asendin
Asendis
CL 67,772
CL-67,772
CL67,772
Demolox
Desmethylloxapine
Défanyl
Tree number(s): D03.633.300.347.500.040
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000657
Scope note: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents, Tricyclic
Neurotransmitter Uptake Inhibitors
Serotonin Uptake Inhibitors
Dopamine Antagonists
Adrenergic Uptake Inhibitors
Registry Number: R63VQ857OT
CAS Type 1 Name: Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(1-piperazinyl)-
Previous Indexing: Dibenzoxazepines (1971-1974)
Piperazines (1971-1974)
Public MeSH Note: 91; was see under DIBENZOXAZEPINES 1975-90
History Note: 91(75); was see under DIBENZOXAZEPINES 1975-90
DeCS ID: 672
Unique ID: D000657
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/27
Revision Date: 2018/07/02
Amoxapine - Preferred
Concept UI M0001008
Scope note The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
Preferred term Amoxapine
Entry term(s) 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Desmethylloxapine
CL-67,772 - Narrower
Concept UI M0354080
Preferred term CL-67,772
Entry term(s) CL 67,772
CL67,772
Demolox - Narrower
Concept UI M0433381
Preferred term Demolox
Asendin - Narrower
Concept UI M0354081
Preferred term Asendin
Entry term(s) Asendis
Défanyl



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