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        | Descriptor English: | Amphetamine | ||||||
| Descriptor Spanish: | 
                                Anfetamina                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Anfetamina | ||||||
| Descriptor French: | Amfétamine | ||||||
| Entry term(s): | 
                                    Amfetamine Amphetamine Sulfate Amphetamine Sulfate (2:1) Centramina Desoxynorephedrin Fenamine Levoamphetamine Mydrial Phenamine Phenopromin Sulfate, Amphetamine Thyramine l Amphetamine l-Amphetamine levo Amphetamine levo-Amphetamine  | 
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| Tree number(s): | 
                                        D02.092.471.683.152.110 | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000661 | ||||||
| Scope note: | A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. | 
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| Annotation: | a specific chem: do not confuse with AMPHETAMINES; d-amphetamine = DEXTROAMPHETAMINE; N-methylamphetamine = METHAMPHETAMINE | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Entry Combination: | 
                                                                            analogs & derivatives:Amphetamines
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| Pharm Action: | 
                                                                                                    Central Nervous System Stimulants Sympathomimetics Dopamine Agents Adrenergic Agents Adrenergic Uptake Inhibitors Dopamine Uptake Inhibitors  | 
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| Registry Number: | CK833KGX7E | ||||||
| CAS Type 1 Name: | Benzeneethanamine, alpha-methyl-, (+-)- | ||||||
| DeCS ID: | 676 | ||||||
| Unique ID: | D000661 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2016/07/05 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals 
| 
                                                             | 
                                
                        
                                                                    
                        Amphetamine                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Centramina                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Fenamine                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Mydrial                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Thyramine                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Amphetamine Sulfate                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        l-Amphetamine                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0001012 | 
                                
| Scope note | A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. | 
| Preferred term | Amphetamine | 
| Entry term(s) | 
                                        
                                                                                            Amfetamine                                                 Desoxynorephedrin Phenamine Phenopromin  | 
                                
| Concept UI | 
                                        
                                        M0432470 | 
                                
| Preferred term | Centramina | 
| Concept UI | 
                                        
                                        M0370892 | 
                                
| Preferred term | Fenamine | 
| Concept UI | 
                                        
                                        M0370893 | 
                                
| Preferred term | Mydrial | 
| Concept UI | 
                                        
                                        M0370894 | 
                                
| Preferred term | Thyramine | 
| Concept UI | 
                                        
                                        M0331305 | 
                                
| Preferred term | Amphetamine Sulfate | 
| Entry term(s) | 
                                        
                                                                                            Amphetamine Sulfate (2:1)                                                 Sulfate, Amphetamine  | 
                                
| Concept UI | 
                                        
                                        M0001013 | 
                                
| Preferred term | l-Amphetamine | 
| Entry term(s) | 
                                        
                                                                                            Levoamphetamine                                                 l Amphetamine levo Amphetamine levo-Amphetamine  | 
                                
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