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Descriptor English: Hydrochlorothiazide
Descriptor Spanish: Hidroclorotiazida
Descriptor hidroclorotiacida
Entry term(s) hidroclorotiazida
Scope note: Diurético tiacídico considerado frecuentemente como el prototipo de esta clase. Reduce la absorción de electrólitos en los túbulos renales. Esto se sigue de aumento de la excreción de agua y electrólitos como sodio, potasio, cloro y magnesio. Se ha utilizado en el tratamiento de procesos graves como edemas, hipertensión, diabetes insípida e hipoparatiroidismo.
Descriptor Portuguese: Hidroclorotiazida
Descriptor French: Hydrochlorothiazide
Entry term(s): Dichlothiazide
Dihydrochlorothiazide
Esidrex
Esidrix
HCTZ
HydroDIURIL
Hypothiazide
Oretic
Sectrazide
Tree number(s): D02.886.590.700.135.261.476
D02.886.655.500.261.476
D03.633.100.174.261.476
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006852
Scope note: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Diuretics
Sodium Chloride Symporter Inhibitors
Registry Number: 0J48LPH2TH
CAS Type 1 Name: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide
DeCS ID: 7005
Unique ID: D006852
NLM Classification: QV 160
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Hydrochlorothiazide - Preferred
Concept UI M0010703
Scope note A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Preferred term Hydrochlorothiazide
Entry term(s) Dichlothiazide
Dihydrochlorothiazide
HCTZ
HydroDIURIL - Narrower
Concept UI M0373033
Preferred term HydroDIURIL
Oretic - Narrower
Concept UI M0373031
Preferred term Oretic
Sectrazide - Narrower
Concept UI M0373030
Preferred term Sectrazide
Esidrix - Narrower
Concept UI M0373034
Preferred term Esidrix
Entry term(s) Esidrex
Hypothiazide - Narrower
Concept UI M0373032
Preferred term Hypothiazide



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