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Descriptor English: Hydroxyurea
Descriptor Spanish: Hidroxiurea
Descriptor hidroxiurea
Entry term(s) hiidroxicarbamida
Scope note: Agente antineoplásico que inhibe la síntesis de ADN merced a la inhibición de la ribonucleósido difosfato reductasa.
Descriptor Portuguese: Hidroxiureia
Descriptor French: Hydroxy-urée
Entry term(s): Hydrea
Hydroxycarbamid
Oncocarbide
Tree number(s): D02.065.950.395
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006918
Scope note: An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Antisickling Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Registry Number: X6Q56QN5QC
CAS Type 1 Name: Urea, hydroxy-
Previous Indexing: Antineoplastic Agents (1966)
Urea (1966)
Public MeSH Note: 68
History Note: 68(67)
DeCS ID: 7097
Unique ID: D006918
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Hydroxyurea - Preferred
Concept UI M0010790
Scope note An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Preferred term Hydroxyurea
Entry term(s) Hydroxycarbamid
Oncocarbide - Narrower
Concept UI M0352404
Preferred term Oncocarbide
Hydrea - Narrower
Concept UI M0010791
Preferred term Hydrea



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