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Descriptor English: Iduronate Sulfatase
Descriptor Spanish: Iduronato Sulfatasa
Descriptor iduronato sulfatasa
Entry term(s) factor correctivo de Hunter
iduronatosulfato sulfohidrolasa
sulfoiduronato sulfatasa
Scope note: Enzima que escinde específicamente el éster sulfato del ácido idurónico. Existe una deficiencia de esta enzima en el síndrome de Hunter, que se caracteriza por un exceso de dermatán sulfato y de heparán sulfato. EC 3.1.6.13.
Descriptor Portuguese: Iduronato Sulfatase
Descriptor French: Iduronate 2-sulfatase
Entry term(s): Corrective Factor, Hunter
Factor, Hunter Corrective
Hunter Corrective Factor
Iduronate Sulfate Sulfatase
Iduronatesulfate Sulfohydrolase
Sulfatase, Iduronate
Sulfatase, Iduronate Sulfate
Sulfatase, Sulfoiduronate
Sulfate Sulfatase, Iduronate
Sulfohydrolase, Iduronatesulfate
Sulfoiduronate Sulfatase
Tree number(s): D08.811.277.352.827.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007066
Scope note: An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Mucopolysaccharidosis II
Registry Number: EC 3.1.6.13
CAS Type 1 Name: L-Iduronate-2-sulfate 2-sulfohydrolase
Previous Indexing: Iduronic Acid (1975)
Sulfatases (1972-1975)
Uronic Acids (1972-1975)
Public MeSH Note: 91; was see under SULFATASES 1976-90
History Note: 91(76); was see under SULFATASES 1976-90
Related: Mucopolysaccharidosis II MeSH
DeCS ID: 7393
Unique ID: D007066
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/25
Revision Date: 2009/07/06
Iduronate Sulfatase - Preferred
Concept UI M0010995
Scope note An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.
Preferred term Iduronate Sulfatase
Entry term(s) Corrective Factor, Hunter
Factor, Hunter Corrective
Hunter Corrective Factor
Iduronate Sulfate Sulfatase
Iduronatesulfate Sulfohydrolase
Sulfatase, Iduronate
Sulfatase, Iduronate Sulfate
Sulfatase, Sulfoiduronate
Sulfate Sulfatase, Iduronate
Sulfohydrolase, Iduronatesulfate
Sulfoiduronate Sulfatase



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