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Descriptor English: Acedapsone
Descriptor Spanish: Acedapsona
Descriptor acedapsona
Entry term(s) DADDS
acetildifenazona
diacetildapsona
Scope note: Sulfona acetilada que se metaboliza lentamente para proporcionar niveles bajos y de larga duración de DAPSONA. Tiene acción antimicrobiana y antipalúdica, pero se utiliza principalmente como un agente leprostático de depósito.
Descriptor Portuguese: Acedapsona
Descriptor French: Acédapsone
Entry term(s): 4',4'''-Sulfonylbis(acetanilide)
4,4' Diacetyldiaminodiphenylsulfone
4,4'-Diacetyldiaminodiphenylsulfone
Acetyldiphenazonum
DADDS
Diacetyldapsone
Hansolar
Rodilone
Sulfadiamine
Tree number(s): D02.886.590.263.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072
Scope note: Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Infective Agents
Antimalarials
Leprostatic Agents
Registry Number: 0GZ72U84TN
CAS Type 1 Name: Acetamide, N,N'-(sulfonyldi-4,1-phenylene)bis-
Previous Indexing: Acetamides (1975)
Acetanilides (1972-1974)
Dapsone/analogs & derivatives (1975)
Sulfones (1972-1974)
Public MeSH Note: 91; was see under DAPSONE 1976-90
History Note: 91(76); was see under DAPSONE 1976-90
DeCS ID: 76
Unique ID: D000072
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/25
Revision Date: 2013/07/08
Acedapsone - Preferred
Concept UI M0000103
Scope note Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
Preferred term Acedapsone
Entry term(s) 4',4'''-Sulfonylbis(acetanilide)
4,4' Diacetyldiaminodiphenylsulfone
4,4'-Diacetyldiaminodiphenylsulfone
Acetyldiphenazonum
DADDS
Diacetyldapsone
Sulfadiamine
Rodilone - Narrower
Concept UI M0352359
Preferred term Rodilone
Hansolar - Narrower
Concept UI M0352360
Preferred term Hansolar



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