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Descriptor English: Ketocholesterols
Descriptor Spanish: Cetocolesteroles
Descriptor cetocolesteroles
Entry term(s) oxocolesteroles
Scope note: Colesterol sustituido en cualquier posición por un grupo cetona. El isómero 7-ceto inhibe la captación del colesterol en las arterias coronarias y en la aorta inhibiendo la actividad de la 3-hidroxi-3-metilglutaril-CoA reductasa.
Descriptor Portuguese: Cetocolesteróis
Descriptor French: Cétocholestérols
Entry term(s): Oxocholesterols
Tree number(s): D04.210.500.247.222.265.450
D04.210.500.247.222.284.800.750
D04.210.500.247.808.197.800.750
D10.570.938.208.825.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007653
Scope note: Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Cholesterol (1966-1974) /analogs & derivatives (1975-1979)
Public MeSH Note: 91; was see under CHOLESTEROL 1980-90
History Note: 91(80); was see under CHOLESTEROL 1980-90
DeCS ID: 7818
Unique ID: D007653
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1979/02/21
Revision Date: 2016/06/06
Ketocholesterols - Preferred
Concept UI M0011986
Scope note Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
Preferred term Ketocholesterols
Entry term(s) Oxocholesterols



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