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Descriptor English: Lysosomes
Descriptor Spanish: Lisosomas
Descriptor Portuguese: Lisossomos
Descriptor French: Lysosomes
Entry term(s): Autolysosome
Autolysosomes
Lysosome
Tree number(s): A11.284.430.214.190.875.190.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008247
Scope note: A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Public MeSH Note: 65
History Note: 65(64)
DeCS ID: 8419
Unique ID: D008247
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/06/09
Lysosomes - Preferred
Concept UI M0012849
Scope note A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Preferred term Lysosomes
Entry term(s) Lysosome
Autolysosomes - Related but not broader or narrower
Concept UI M000655238
Scope note Structures formed from the fusion of lysosomes and AUTOPHAGOSOMES that results in the digestion of the autophagosome and its content.
Preferred term Autolysosomes
Entry term(s) Autolysosome



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