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Descriptor in English: Mannitol
Descriptor in Spanish: Manitol
Descriptor in Portuguese: Manitol
Descriptor in French: Mannitol
Entry term(s): (L)-Mannitol
Osmitrol
Osmofundin
Tree number(s): D02.033.800.609
D09.853.609
Scope note: A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
DeCS UI: 8525
Descriptor UI: D008353
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Mannitol - Preferred
Concept UI M0012995
Scope note A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Preferred term Mannitol
Osmitrol - Narrower
Concept UI M0337705
Preferred term Osmitrol
Osmofundin - Narrower
Concept UI M0012996
Preferred term Osmofundin
(L)-Mannitol - Related but not broader or narrower
Concept UI M0330105
Preferred term (L)-Mannitol



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