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Descripteur en français: Séquence instable d'ADN
Descripteur en anglais: DNA Sequence, Unstable
Descripteur en espagnol: Secuencia de ADN Inestable
Descripteur secuencia de ADN inestable
Synonymes secuencia inestable de ADN
Note d'application: Región de ADN que es muy polimorfa y tiene tendencia a presentar rupturas, reordenamiento de cadenas y otras MUTACIONES debido a la naturaleza de su secuencia. Con frecuencia estas zonas contienen secuencias palindrómicas o repetitivas (SECUENCIAS REPETITIVAS DEL ÁCIDO NUCLEICO). La variabilidad de la estabilidad de la secuencia del ADN se observa en los SITIOS FRÁGILES DE LOS CROMOSOMAS.
Descripteur en portugais: Sequência de DNA Instável
Synonymes: DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences
Code(s) d'arborescence: G05.360.340.024.189
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D043243
Note d'application: A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Qualificatifs autorisés: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Note publique MeSH: 2004(1998); see TRINUCLEOTIDE REPEAT EXPANSION 1999-2003
Note historique: 2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003
Version alternative: DNA SEQ UNSTABLE
Voir aussi le(s) descripteur(s): Chromosome Fragility MeSH
Genomic Instability MeSH
Identifiant DeCS: 38394
ID du Descripteur: D043243
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/2004
Date d'entrée: 09/07/2003
Date de révision: 08/07/2008
DNA Sequence, Unstable - Concept préféré
Concept UI M0029212
Note d'application A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Terme préféré DNA Sequence, Unstable
Synonymes DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences



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