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Descripteur en français: Anoctamines
Descripteur en anglais: Anoctamins
Descripteur en espagnol: Anoctaminas
Descripteur anoctaminas
Synonymes anoctamina
familia de proteínas TMEM16
proteínas TMEM16
Note d'application: Familia de proteínas transmembranarias que actúan principalmente como canales de cloruro activados por calcio. Estructuralmente forman un heterodímero en el que cada subunidad consta de ocho hélices transmembranarias con los extremos N y C expuestos al citosol. Las regiones entre las hélices 5 y 7 son importantes para la formación de poros iónicos y la unión a los iones calcio.
Descripteur en portugais: Anoctaminas
Synonymes: Anoctamin
Protein Family, TMEM16
TMEM16 Protein Family
TMEM16 Proteins
Code(s) d'arborescence: D12.776.157.530.400.175.032
D12.776.543.550.450.175.032
D12.776.543.585.400.175.032
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D000075368
Note d'application: A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Qualificatifs autorisés: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Indexation précédente: Chloride Channels (2009-2017)
Note publique MeSH: 2018
Note historique: 2018
Identifiant DeCS: 57079
ID du Descripteur: D000075368
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/2018
Date d'entrée: 11/07/2017
Date de révision: 24/05/2017
Anoctamins - Concept préféré
Concept UI M000630244
Note d'application A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Terme préféré Anoctamins
Synonymes Anoctamin
Protein Family, TMEM16
TMEM16 Protein Family
TMEM16 Proteins



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