Descriptor English: Oncogenes
Descriptor Spanish: Oncogenes
Descriptor Portuguese: Oncogenes
Descriptor French: Oncogènes
Entry term(s): Gènes transformants
Tree number(s): G05.360.340.024.340.375.500
RDF Unique Identifier:
Scope note: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Annotation: "oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual; do not confuse with GENES, NEOPLASM
Allowable Qualifiers: DE effets des médicaments et des substances chimiques
ES éthique
GE génétique
IM immunologie
PH physiologie
RE effets des radiations
DeCS ID: 10040
Unique ID: D009857
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/04/22
Revision Date: 2008/07/08
Oncogènes - Preferred
Concept UI M0015298
Preferred term Oncogènes
Entry term(s) Gènes transformants

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