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Descriptor English: Genes, Tumor Suppressor
Descriptor Spanish: Genes Supresores de Tumor
Descriptor genes supresores de tumores
Entry term(s) antioncogenes
emerogenes
genes supresores de metástasis
genes supresores de tumor
genes supresores del crecimiento
genes supresores del cáncer
Scope note: Genes que inhiben la expresión del fenotipo tumorigénico. Normalmente están implicados en el control del crecimiento celular. Cuando se inactivan o se pierden desaparece una barrera a la proliferación normal y se posibilita el crecimiento desregulado.
Descriptor Portuguese: Genes Supressores de Tumor
Descriptor French: Gènes suppresseurs de tumeur
Entry term(s): Anti Oncogenes
Anti-Oncogene
Anti-Oncogenes
Antioncogene
Antioncogenes
Cancer Suppressor Gene
Cancer Suppressor Genes
Emerogene
Emerogenes
Gene, Cancer Suppressor
Gene, Growth Suppressor
Gene, Metastasis Suppressor
Gene, Onco-Suppressor
Gene, Tumor Suppressing
Gene, Tumor Suppressor
Genes, Cancer Suppressor
Genes, Growth Suppressor
Genes, Metastasis Suppressor
Genes, Onco Suppressor
Genes, Onco-Suppressor
Genes, Tumor Suppressing
Growth Suppressor Gene
Growth Suppressor Genes
Metastasis Suppressor Gene
Metastasis Suppressor Genes
Onco-Suppressor Gene
Onco-Suppressor Genes
Oncogene, Recessive
Oncogenes, Recessive
Recessive Oncogene
Recessive Oncogenes
Suppressor Gene, Cancer
Suppressor Gene, Growth
Suppressor Gene, Metastasis
Suppressor Genes, Cancer
Suppressor Genes, Growth
Suppressor Genes, Metastasis
Tumor Suppressing Gene
Tumor Suppressing Genes
Tumor Suppressor Gene
Tumor Suppressor Genes
Tree number(s): G05.360.340.024.340.375.249
G05.360.340.024.340.415.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016147
Scope note: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Annotation: Manual 24.4.4.3
Allowable Qualifiers: DE drug effects
ES ethics
PH physiology
RE radiation effects
Previous Indexing: Suppression, Genetic (1986-1990)
Public MeSH Note: 2002; see GENES, SUPPRESSOR, TUMOR 1991-2001
History Note: 2002 (1991)
Related: Tumor Suppressor Proteins MeSH
DeCS ID: 28963
Unique ID: D016147
NLM Classification: QZ 210
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/07
Revision Date: 2008/07/08
Genes, Tumor Suppressor - Preferred
Concept UI M0024663
Scope note Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Preferred term Genes, Tumor Suppressor
Entry term(s) Anti Oncogenes
Anti-Oncogene
Anti-Oncogenes
Antioncogene
Antioncogenes
Cancer Suppressor Gene
Cancer Suppressor Genes
Emerogene
Emerogenes
Gene, Cancer Suppressor
Gene, Onco-Suppressor
Gene, Tumor Suppressing
Gene, Tumor Suppressor
Genes, Cancer Suppressor
Genes, Onco Suppressor
Genes, Onco-Suppressor
Genes, Tumor Suppressing
Onco-Suppressor Gene
Onco-Suppressor Genes
Oncogene, Recessive
Oncogenes, Recessive
Recessive Oncogene
Recessive Oncogenes
Suppressor Gene, Cancer
Suppressor Genes, Cancer
Tumor Suppressing Gene
Tumor Suppressing Genes
Tumor Suppressor Gene
Tumor Suppressor Genes
Metastasis Suppressor Genes - Related but not broader or narrower
Concept UI M0372036
Preferred term Metastasis Suppressor Genes
Entry term(s) Gene, Metastasis Suppressor
Genes, Metastasis Suppressor
Metastasis Suppressor Gene
Suppressor Gene, Metastasis
Suppressor Genes, Metastasis
Growth Suppressor Genes - Broader
Concept UI M0372037
Preferred term Growth Suppressor Genes
Entry term(s) Gene, Growth Suppressor
Genes, Growth Suppressor
Growth Suppressor Gene
Suppressor Gene, Growth
Suppressor Genes, Growth



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