Search
Descriptor in English: Oncogenes
Descriptor in Spanish: Oncogenes
Descriptor in Portuguese: Oncogenes
Descriptor in French: Oncogènes
Entry term(s): Gene, Transforming
Genes, Transforming
Oncogene
Transforming Gene
Transforming Genes
Tree number(s): G05.360.340.024.340.375.500
Scope note: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Annotation: "oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
History Note: 83
DeCS UI: 10040
Descriptor UI: D009857
Date Established: 1983/01/01
Date of Entry: 1982/04/22
Revision Date: 2008/07/08
Oncogenes - Preferred
Concept UI M0015298
Scope note Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Preferred term Oncogenes
Entry term(s) Gene, Transforming
Genes, Transforming
Oncogene
Transforming Gene
Transforming Genes



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey