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Descriptor English: Parkinson Disease
Descriptor Spanish: Enfermedad de Parkinson
Descriptor enfermedad de Parkinson
Entry term(s) enfermedad de Parkinson con cuerpos de Lewy
enfermedad de Parkinson idiopática
parkinsonismo primario
parálisis agitante
Scope note: Enfermedad neurológica degenerativa y progresiva caracterizada por TEMBLOR, que es máximo durante el reposo, retropulsión (es decir, tendencia a caerse hacia atrás), rigidez, postura estática, lentitud de los movimientos voluntarios y expresión facial en máscara. Las características anatomopatológicas incluyen pérdida de las neuronas que contienen melanina de la sustancia negra y de otros núcleos pigmentados del tronco encefálico. Los CUERPOS DE LEWY se hallan en la sustancia negra y en el locus coeruleus y pueden también encontrarse en una afección relacionada, la ENFERMEDAD POR CUERPOS DE LEWY, que se caracteriza por demencia en combinación con grados variables de parkinsonismo. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Descriptor Portuguese: Doença de Parkinson
Descriptor French: Maladie de Parkinson
Entry term(s): Idiopathic Parkinson Disease
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Lewy Body Parkinson's Disease
Paralysis Agitans
Parkinson Disease, Idiopathic
Parkinson's Disease
Parkinson's Disease, Idiopathic
Parkinson's Disease, Lewy Body
Parkinsonism, Primary
Primary Parkinsonism
Tree number(s): C10.228.140.079.862.500
C10.228.662.600.400
C10.574.928.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010300
Scope note: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Annotation: drug ther: consider also ANTIPARKINSON AGENTS; /chem ind = PARKINSON DISEASE, SECONDARY/chem ind
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Entry Combination: chemically induced:Parkinson Disease, Secondary /chemically induced
Public MeSH Note: 1979; see PARKINSONISM 1967-1978, see PARALYSIS AGITANS 1963-1966
History Note: 1979(1963)
Entry Version: PARKINSON DIS
Related: Lewy Bodies MeSH
DeCS ID: 10489
Unique ID: D010300
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1967/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Parkinson Disease - Preferred
Concept UI M0015963
Scope note A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Preferred term Parkinson Disease
Entry term(s) Idiopathic Parkinson Disease
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Lewy Body Parkinson's Disease
Paralysis Agitans
Parkinson Disease, Idiopathic
Parkinson's Disease
Parkinson's Disease, Idiopathic
Parkinson's Disease, Lewy Body
Parkinsonism, Primary
Primary Parkinsonism



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