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Descriptor English: Pentazocine
Descriptor Spanish: Pentazocina
Descriptor pentazocina
Scope note: El primer analgésico mezcla de agonista-antagonista que se comercializó. Es un agonista de los receptores kappa y sigma y tiene una acción antagonista débil del receptor mu.
Descriptor Portuguese: Pentazocina
Descriptor French: Pentazocine
Entry term(s): Fortral
Hydrochloride, Pentazocine
Lactate, Pentazocine
Lexir
Pentazocine Hydrochloride
Pentazocine Lactate
Talwin
Tree number(s): D03.132.577.249.106.700
D04.615.723.795.106.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010423
Scope note: The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics, Opioid
Adjuvants, Anesthesia
Narcotic Antagonists
Narcotics
Registry Number: RP4A60D26L
CAS Type 1 Name: 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2alpha,6alpha,11R*)-
Public MeSH Note: 66
History Note: 66(64)
DeCS ID: 10617
Unique ID: D010423
NLM Classification: QV 89
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Pentazocine - Preferred
Concept UI M0016179
Scope note The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Preferred term Pentazocine
Lexir - Narrower
Concept UI M0352864
Preferred term Lexir
Pentazocine Lactate - Narrower
Concept UI M0329814
Preferred term Pentazocine Lactate
Entry term(s) Lactate, Pentazocine
Talwin - Narrower
Concept UI M0016180
Preferred term Talwin
Fortral - Narrower
Concept UI M0016181
Preferred term Fortral
Pentazocine Hydrochloride - Narrower
Concept UI M0329815
Preferred term Pentazocine Hydrochloride
Entry term(s) Hydrochloride, Pentazocine



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