DeCS

Descriptor English:

Pentylenetetrazole

Descriptor Spanish:

Pentilenotetrazol

Spanish from Spain

Descriptor	pentilenotetrazol
Entry term(s)	cardiazol leptazol metrazol pentametilenotetrazol pentetrazol
Scope note:	Fármaco que muestra actividad como estimulante del sistema nervioso central y respiratorio. Es considerado un antagonista GABA no competitivo. El pentilenotetrazol se ha utilizado experimentalmente para estudiar el fenómeno de los ataques y para identificar fármacos que puedan controlar la susceptibilidad a los ataques.

Descriptor Portuguese:

Pentilenotetrazol

Descriptor French:

Pentétrazol

Tree number(s):

D03.383.066.600

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D010433

Scope note:

A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Convulsants
GABA Antagonists

Registry Number:

WM5Z385K7T

CAS Type 1 Name:

5H-Tetrazolo(1,5-a)azepine, 6,7,8,9-tetrahydro-

DeCS ID:

10627

Unique ID:

D010433

Documents indexed in the Virtual Health Library (VHL):

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