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Descriptor English: Argininosuccinate Lyase
Descriptor Spanish: Argininosuccinatoliasa
Descriptor argininosuccinato liasa
Entry term(s) argininosuccinasa
Scope note: Enzima del ciclo de la urea que escinde el argininosuccinato en fumarato más arginina. Su ausencia en el hombre conduce a la enfermedad metabólica conocida como acidemia argininosuccínica. EC 4.3.2.1.
Descriptor Portuguese: Argininossuccinato Liase
Descriptor French: Argininosuccinate lyase
Entry term(s): Argininosuccinase
Lyase, Argininosuccinate
Tree number(s): D08.811.520.232.300.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001123
Scope note: An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC ACIDURIA in man. EC 4.3.2.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Argininosuccinic Aciduria
Registry Number: EC 4.3.2.1
CAS Type 1 Name: N-(L-Argininosuccinate) arginine-lyase
Previous Indexing: Arginine (1973-1974)
Lyases (1973-1974)
Succinates (1973-1974)
Public MeSH Note: 1991; see LYASES 1975-1990
History Note: 1991(1975); use LYASES 1975-1990
Related: Argininosuccinic Aciduria MeSH
DeCS ID: 1126
Unique ID: D001123
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2009/07/06
Argininosuccinate Lyase - Preferred
Concept UI M0001687
Scope note An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC ACIDURIA in man. EC 4.3.2.1.
Preferred term Argininosuccinate Lyase
Entry term(s) Argininosuccinase
Lyase, Argininosuccinate



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