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Descriptor English: Podophyllin
Descriptor Spanish: Podofilino
Descriptor podofilino
Entry term(s) podofilina
Scope note: Extracto cáustico de las raíces del Podophyllum peltatum y P. emodi. Contiene PODOFILOTOXINA y sus congéneres y es muy irritante para las membranas mucosas y la piel. La podofilina es un potente purgante que puede causar daño al sistema nervioso central y ser teratógeno. Se utiliza en verrugas, neoplasias cutáneas y en la queratosis senil.
Descriptor Portuguese: Podofilina
Descriptor French: Podophylline
Entry term(s): Podophyllum Resin
Resin, Podophyllum
Tree number(s): D20.215.784.500.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011033
Scope note: Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Phytogenic
Caustics
Keratolytic Agents
Registry Number: 9000-55-9
Public MeSH Note: 72; was see under PODOPHYLLUM 1963-71
Online Note: search PODOPHYLLUM 1966-71
History Note: 72(64); was see under PODOPHYLLUM 1963-71
DeCS ID: 11463
Unique ID: D011033
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05
Podophyllin - Preferred
Concept UI M0017086
Scope note Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.
Preferred term Podophyllin
Entry term(s) Podophyllum Resin
Resin, Podophyllum



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