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Descriptor English: Pralidoxime Compounds
Descriptor Spanish: Compuestos de Pralidoxima
Descriptor compuestos de pralidoxima
Entry term(s) compuestos de 2-PAM
compuestos de aldoxima de metilpiridina
Scope note: Diversas sales de oxima de amonio cuaternario que reconstituyen la acetilcolinesterasa inactivada, especialmente en la unión neuromuscular y pueden causar bloqueo neuromuscular. Se utilizan como antídotos en la intoxicación por organofosforados como cloruros, yoduros, metanosulfonatos (mesilatos) y otras sales.
Descriptor Portuguese: Compostos de Pralidoxima
Descriptor French: Composés de pralidoxime
Entry term(s): 2 PAM Compounds
2-PAM Compounds
Compounds, 2-PAM
Compounds, Pralidoxime
Pyridine Aldoxime Methyl Compounds
Tree number(s): D02.092.570.665.535
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011220
Scope note: Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 65
History Note: 65(63)
Entry Version: PRALIDOXIME CPDS
DeCS ID: 11657
Unique ID: D011220
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2000/06/22
Pralidoxime Compounds - Preferred
Concept UI M0017435
Scope note Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
Preferred term Pralidoxime Compounds
Entry term(s) 2 PAM Compounds
2-PAM Compounds
Compounds, 2-PAM
Compounds, Pralidoxime
Pyridine Aldoxime Methyl Compounds



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