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Descriptor English: Prednimustine
Descriptor Spanish: Prednimustina
Descriptor prednimustina
Scope note: Ester de CLORAMBUCILO y PREDNISOLONA utilizado como una combinación de agente alquilante y esteroide sintético para tratar diversas leucemias y otras neoplasias. Ocasiona toxicidad gastrointestinal y en la médula ósea.
Descriptor Portuguese: Prednimustina
Descriptor French: Prednimustine
Entry term(s): Leo 1031
Leo-1031
Leo1031
NSC 134087
NSC-134087
NSC134087
Sterecyt
Stereocyt
Stéréocyt
Tree number(s): D02.455.526.728.650.156.700
D04.210.500.745.432.769.795.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011238
Scope note: Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Registry Number: 9403SIO2S8
CAS Type 1 Name: Pregna-1,4-diene-3,20-dione, 21-(4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)-11,17-dihydroxy-, (11beta)-
Previous Indexing: Chlorambucil (1966-1974) /analogs & derivatives (1975-1979)
Prednisolone (1966-1974) /analogs & derivatives (1975-1979)
Public MeSH Note: 91; was see under CHLORAMBUCIL 1980-90
History Note: 91(80); was see under CHLORAMBUCIL 1980-90
DeCS ID: 11672
Unique ID: D011238
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1979/05/30
Revision Date: 2017/05/24
Prednimustine - Preferred
Concept UI M0017459
Scope note Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.
Preferred term Prednimustine
NSC-134087 - Narrower
Concept UI M0351884
Preferred term NSC-134087
Entry term(s) NSC 134087
NSC134087
Stereocyt - Narrower
Concept UI M0351885
Preferred term Stereocyt
Entry term(s) Sterecyt
Stéréocyt
Leo-1031 - Narrower
Concept UI M0351880
Preferred term Leo-1031
Entry term(s) Leo 1031
Leo1031



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