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Descriptor English: Nitrogen Mustard Compounds
Descriptor Spanish: Compuestos de Mostaza Nitrogenada
Descriptor compuestos de mostaza nitrogenada
Scope note: Grupo de agentes alquilantes derivados del gas mostaza en los cuales el azufre está sustituido por nitrógeno. Fueron antiguamente utilizados como tóxicos y vesicantes, pero en la actualidad funcionan como agentes antineoplásicos. Estos compuestos son también poderosos mutágenos, teratógenos, inmunosupresores y carcinógenos.
Descriptor Portuguese: Compostos de Mostarda Nitrogenada
Descriptor French: Moutardes à l'azote
Entry term(s): Compounds, Nitrogen Mustard
Mustard Compounds, Nitrogen
Tree number(s): D02.455.526.728.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009588
Scope note: A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
Annotation: do not confuse with NITROGEN MUSTARD, a specific chemical
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Entry Version: NITROGEN MUSTARD CPDS
DeCS ID: 9773
Unique ID: D009588
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 1999/11/03
Nitrogen Mustard Compounds - Preferred
Concept UI M0014901
Scope note A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
Preferred term Nitrogen Mustard Compounds
Entry term(s) Compounds, Nitrogen Mustard
Mustard Compounds, Nitrogen



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