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Descriptor English: Primaquine
Descriptor Spanish: Primaquina
Descriptor primaquina
Scope note: Aminoquinolina que se administra por vía oral para producir una curación radical y prevenir la recaída de la malaria vivax y ovale, depués del tratamiento con un esquizontócida sanguíneo. También se ha utilizado para prevenir la trasmisión de la malaria falciparum en aquellos que regresan a áreas donde existe posibilidad de recaídas de la malaria. Los efectos secundarios incluyen anemias y alteraciones gastrointestinales. (Martindale, The Extra Pharmacopeia, 30th ed, p404)
Descriptor Portuguese: Primaquina
Descriptor French: Primaquine
Entry term(s): Diphosphate, Primaquine
Phosphate, Primaquine
Primacin
Primaquine Diphosphate
Primaquine Phosphate
Tree number(s): D03.633.100.810.050.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011319
Scope note: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimalarials
Registry Number: MVR3634GX1
CAS Type 1 Name: 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-
DeCS ID: 11755
Unique ID: D011319
NLM Classification: QV 258
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Primaquine - Preferred
Concept UI M0017573
Scope note An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
Preferred term Primaquine
Primaquine Phosphate - Narrower
Concept UI M0017575
Preferred term Primaquine Phosphate
Entry term(s) Phosphate, Primaquine
Primacin - Narrower
Concept UI M0475721
Preferred term Primacin
Primaquine Diphosphate - Narrower
Concept UI M0329757
Preferred term Primaquine Diphosphate
Entry term(s) Diphosphate, Primaquine



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