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Descriptor English: 4-Hydroxyaminoquinoline-1-oxide
Descriptor Spanish: 4-Hidroxiaminoquinolina-1-Óxido
Descriptor Portuguese: 4-Hidroxiaminoquinolina-1-Óxido
Descriptor French: 4-Hydroxyamino quinoléine 1-oxyde
Entry term(s): 4 Hydroxyaminoquinoline 1 oxide
4 Hydroxyaminoquinoline N oxide
4-Hydroxyaminoquinoline-N-oxide
Tree number(s): D02.092.570.450
D03.633.100.810.050.440
D03.661.243.320
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015108
Scope note: A potent mutagen and carcinogen. It is a reduction product of 4-NITROQUINOLINE-1-OXIDE. It binds with nucleic acids and inactivates both bacteria and bacteriophage.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Carcinogens
Mutagens
Registry Number: 4637-56-3
CAS Type 1 Name: 4-Quinolinamine, N-hydroxy-, 1-oxide
Previous Indexing: Cyclic N-Oxides (1972-1974)
Hydroxylamines (1974)
Quinolines (1972-1974)
Public MeSH Note: 91; was see under AMINOQUINOLINES 1975-90
History Note: 91(75); was see under AMINOQUINOLINES 1975-90
DeCS ID: 7038
Unique ID: D015108
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/14
Revision Date: 2016/05/27
4-Hydroxyaminoquinoline-1-oxide - Preferred
Concept UI M0023239
Scope note A potent mutagen and carcinogen. It is a reduction product of 4-NITROQUINOLINE-1-OXIDE. It binds with nucleic acids and inactivates both bacteria and bacteriophage.
Preferred term 4-Hydroxyaminoquinoline-1-oxide
Entry term(s) 4 Hydroxyaminoquinoline 1 oxide
4 Hydroxyaminoquinoline N oxide
4-Hydroxyaminoquinoline-N-oxide



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