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Descriptor English: Propylthiouracil
Descriptor Spanish: Propiltiouracilo
Descriptor propiltiouracilo
Scope note: Tiourea usada como agente antitiroideo. El propiltiuracilo inhibe la síntesis de tiroxina y la conversión periférica de tiroxina a triyodotironina. Se utiliza en el tratamiento del hipertiroidismo. (Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Descriptor Portuguese: Propiltiouracila
Descriptor French: Propylthiouracile
Entry term(s): 6 Propyl 2 Thiouracil
6-Propyl-2-Thiouracil
Tree number(s): D03.383.742.698.875.842.708
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011441
Scope note: A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Annotation: a thyroid antag
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Antithyroid Agents
Registry Number: 721M9407IY
CAS Type 1 Name: 4(1H)-Pyrimidinone, 2,3-dihydro-6-propyl-2-thioxo-
DeCS ID: 11873
Unique ID: D011441
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Propylthiouracil - Preferred
Concept UI M0017784
Scope note A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Preferred term Propylthiouracil
Entry term(s) 6 Propyl 2 Thiouracil
6-Propyl-2-Thiouracil



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