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Descriptor English: Prostaglandins E
Descriptor Spanish: Prostaglandinas E
Descriptor prostaglandinas E
Entry term(s) PGE
Scope note: Ácido(11 alfa,13E,15S)-11,15-dihidroxi-9-oxoprost-13-en-1-oico (PGE(1)); ácido (5Z,11 alfa,13E,15S)-11,15-dihidroxi-9-oxoprosta-5,13-dien-1-oico (PGE(2)); y ácido (5Z,11 afha,13E,15S,17Z)-11,15-dihidroxi-9-oxoprosta-5,13,17-trien-1-oico (PGE(3)). Tres de las seis prostaglandinas naturales. Se consideran primarias porque ninguna de ellas deriva de otra en los organismos vivos. Aisladas originalmente del líquido y vesículas seminales del carnero, se encuentran en muchos órganos y tejidos y desempeñan un papel principal en la mediación de diversas actividades fisiológicas.
Descriptor Portuguese: Prostaglandinas E
Descriptor French: Prostaglandines E
Entry term(s): PGE
Tree number(s): D10.251.355.255.550.250
D23.469.050.175.725.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011458
Scope note: (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
Annotation: /chem syn permitted: do not convert to PROSTAGLANDINS E, SYNTHETIC
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Prostaglandins E, Synthetic
Previous Indexing: Prostaglandins (1966-1974)
Public MeSH Note: 75
History Note: 75
DeCS ID: 11891
Unique ID: D011458
NLM Classification: QU 91
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1975/09/01
Date of Entry: 1974/11/11
Revision Date: 2016/06/28
Prostaglandins E - Preferred
Concept UI M0017810
Scope note (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
Preferred term Prostaglandins E
Entry term(s) PGE



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