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Descriptor English: Scleroderma, Systemic
Descriptor Spanish: Esclerodermia Sistémica
Descriptor esclerodermia sistémica
Entry term(s) esclerosis sistémica
Scope note: Trastorno crónico multisistémico del TEJIDO CONJUNTIVO. Se caracteriza por ESCLEROSIS en la PIEL, PULMONES, CORAZON, TRACTO GASTROINTESTINAL, RIÑONES, y SISTEMA MUSCULOESQUELÉTICO. Otras características importantes son enfermedad de los pequeños VASOS SANGUINEOS y presencia de AUTOANTICUERPOS. El trastorno recibe este nombre por su característica mas prominente (piel dura), y se clasifica en subgrupos según la amplitud del engrosamiento cutáneo: ESCLERODERMIA LIMITADA y ESCLERODERMIA DIFUSA.
Descriptor Portuguese: Escleroderma Sistêmico
Descriptor French: Sclérodermie systémique
Entry term(s): Sclerosis, Systemic
Systemic Scleroderma
Systemic Sclerosis
Tree number(s): C17.300.799
C17.800.784
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012595
Scope note: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Annotation: note specific indentations and SCLERODERMA, LOCALIZED
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Public MeSH Note: 1971; SCLERODERMA was heading 1963-70
History Note: 1971
DeCS ID: 12976
Unique ID: D012595
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1971/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Scleroderma, Systemic - Preferred
Concept UI M0019543
Scope note A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Preferred term Scleroderma, Systemic
Entry term(s) Sclerosis, Systemic
Systemic Scleroderma
Systemic Sclerosis



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