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Descriptor English: Streptonigrin
Descriptor Spanish: Estreptonigrina
Descriptor estreptonigrina
Entry term(s) bruneomicina
rufocromomicina
Scope note: Antibiótico citotóxico complejo obtenido del Streptomyces flocculus o S. rufochronmogenus. Se utiliza en el carcinoma avanzado y causa leucopenia.
Descriptor Portuguese: Estreptonigrina
Descriptor French: Streptonigrine
Entry term(s): Brunemycin
Bruneomycin
NSC 45383
NSC-45383
NSC45383
Nigrin
Rufocromomycin
Tree number(s): D03.066.707.768
D03.383.725.705.768
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013308
Scope note: Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Registry Number: 261Q3JB310
CAS Type 1 Name: 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-
Public MeSH Note: 73
History Note: 73(65)
DeCS ID: 13696
Unique ID: D013308
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/01
Streptonigrin - Preferred
Concept UI M0020597
Scope note Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia.
Preferred term Streptonigrin
Entry term(s) Brunemycin
Bruneomycin
Rufocromomycin
NSC-45383 - Narrower
Concept UI M0352655
Preferred term NSC-45383
Entry term(s) NSC 45383
NSC45383
Nigrin - Narrower
Concept UI M0361650
Preferred term Nigrin



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