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Descriptor English: Strychnine
Descriptor Spanish: Estricnina
Descriptor estricnina
Scope note: Alcaloide que se encuentra en las semillas de la STRYCHNOS NUX-VOMICA. Es un antagonista competitivo de los receptores de glicina y por lo tanto un convulsivante. Se ha utilizado como analéptico, en el tratamiento de la hiperglicemia no cetósica, en la apnea del sueño y como veneno para ratas.
Descriptor Portuguese: Estricnina
Descriptor French: Strychnine
Entry term(s): Nitrate, Strychnine
Strychnine Nitrate
Tree number(s): D03.132.436.681.722
D03.633.100.473.402.681.722
D03.633.100.496.500.500.681.722
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013331
Scope note: An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Convulsants
Poisons
Glycine Agents
Registry Number: H9Y79VD43J
CAS Type 1 Name: Strychnidin-10-one
Public MeSH Note: NUX VOMICA was heading 1963-78
Online Note: use STRYCHNINE to search NUX VOMICA 1966-78
History Note: NUX VOMICA was heading 1963-78
DeCS ID: 13718
Unique ID: D013331
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/01
Strychnine - Preferred
Concept UI M0020628
Scope note An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.
Preferred term Strychnine
Strychnine Nitrate - Narrower
Concept UI M0020629
Preferred term Strychnine Nitrate
Entry term(s) Nitrate, Strychnine



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