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Descriptor English: Synapses
Descriptor Spanish: Sinapsis
Descriptor Portuguese: Sinapses
Descriptor French: Synapses
Entry term(s): Synapse
Tree number(s): A08.850
A11.284.149.165.420.780
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013569
Scope note: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Annotation: note specifics; IMMUNOLOGICAL SYNAPSES is also available; / physiol: consider also SYNAPTIC TRANSMISSION; do not confuse with SYNAPSIS see CHROMOSOME PAIRING
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
UL ultrastructure
VI virology
Related: Gap Junctions MeSH
Synaptic Transmission MeSH
Synaptosomes MeSH
DeCS ID: 13949
Unique ID: D013569
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2008/07/08
Synapses - Preferred
Concept UI M0020950
Scope note Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Preferred term Synapses
Entry term(s) Synapse



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