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Descriptor in English: Synapses
Descriptor in Spanish: Sinapsis
Descriptor in Portuguese: Sinapses
Descriptor in French: Synapses
Entry term(s): Synapse
Tree number(s): A08.850
A11.284.149.165.420.780
Scope note: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Annotation: note specifics; IMMUNOLOGICAL SYNAPSES is also available; / physiol: consider also SYNAPTIC TRANSMISSION; do not confuse with SYNAPSIS see CHROMOSOME PAIRING
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
UL ultrastructure
VI virology
See also the descriptors: Gap Junctions MeSH
Synaptic Transmission MeSH
Synaptosomes MeSH
DeCS UI: 13949
Descriptor UI: D013569
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2008/07/08
Synapses - Preferred
Concept UI M0020950
Scope note Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Preferred term Synapses
Entry term(s) Synapse



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