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Descriptor English: Azauridine
Descriptor Spanish: Azauridina
Descriptor azauridina
Scope note: Nucleósido triacínico que se utiliza como antimetabolito antineoplásico. Interfiere con la biosíntesis de pirimidina previniendo así la formación de ácidos nucleicos celulares. También es efectiva como antipsoriásico.
Descriptor Portuguese: Azauridina
Descriptor French: 6-Azauridine
Entry term(s): 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
6 Azauridine
6-Azauridine
Tree number(s): D02.145.451
D03.383.742.680.852.176
D13.570.685.852.176
D13.570.800.892.176
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001380
Scope note: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Dermatologic Agents
Registry Number: 7BVB29RCPR
CAS Type 1 Name: 1,2,4-Triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl-
Previous Indexing: Antimetabolites (1966-1971)
Uridine (1966-1971)
Public MeSH Note: 73
History Note: 73(72)
DeCS ID: 1396
Unique ID: D001380
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/27
Azauridine - Preferred
Concept UI M0002068
Scope note A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Preferred term Azauridine
Entry term(s) 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
6 Azauridine
6-Azauridine



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