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Descriptor English: Azacitidine
Descriptor Spanish: Azacitidina
Descriptor azacitidina
Scope note: Análogo de pirimidina que inhibe la ADN metiltransferasa afectando a la metilación del ADN. También es un antimetabolito de la citidina que se incorpora principalmente al ARN. La azacitidina ha sido utilizada como agente antineoplásico.
Descriptor Portuguese: Azacitidina
Descriptor French: Azacitidine
Entry term(s): 5 Azacytidine
5-Azacytidine
Azacytidine
NSC 102816
NSC-102816
NSC102816
Vidaza
Tree number(s): D02.145.150
D03.383.742.680.245.217
D13.570.685.245.217
D13.570.800.286.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001374
Scope note: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Enzyme Inhibitors
Registry Number: M801H13NRU
CAS Type 1 Name: 1,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-
Previous Indexing: Nucleosides (1966-1971)
Triazines (1966-1971)
Public MeSH Note: 96; was AZACYTIDINE 1974-95
History Note: 96; was AZACYTIDINE 1972-95 (Prov 1972-73)
DeCS ID: 1386
Unique ID: D001374
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Azacitidine - Preferred
Concept UI M0002060
Scope note A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.
Preferred term Azacitidine
Entry term(s) 5 Azacytidine
5-Azacytidine
Azacytidine
Vidaza - Narrower
Concept UI M0473506
Preferred term Vidaza
NSC-102816 - Narrower
Concept UI M0351376
Preferred term NSC-102816
Entry term(s) NSC 102816
NSC102816



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