Descriptor English: | Tamoxifen | ||||||
Descriptor Spanish: |
Tamoxifeno
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Descriptor Portuguese: | Tamoxifeno | ||||||
Descriptor French: | Tamoxifène | ||||||
Entry term(s): |
Citrate, Tamoxifen ICI 46,474 ICI 46474 ICI 47699 ICI-46,474 ICI-46474 ICI-47699 ICI46,474 ICI46474 ICI47699 Nolvadex Novaldex Soltamox Tamoxifen Citrate Tomaxithen Zitazonium |
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Tree number(s): |
D02.455.426.559.389.150.700.900 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013629 | ||||||
Scope note: | One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Estrogen Antagonists Antineoplastic Agents, Hormonal Selective Estrogen Receptor Modulators Bone Density Conservation Agents |
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Registry Number: | 094ZI81Y45 | ||||||
CAS Type 1 Name: | Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)- | ||||||
Previous Indexing: |
Dimethylamines (1973-1974) Phenyl Ethers (1974) Stilbenes (1966-1974) |
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Public MeSH Note: | 78; was see under STILBENES 1975-77 |
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History Note: | 78(75); was see under STILBENES 1975-77 |
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DeCS ID: | 14010 | ||||||
Unique ID: | D013629 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1978/01/01 | ||||||
Date of Entry: | 1974/11/11 | ||||||
Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals
|
Tamoxifen
- Preferred
ICI-47699
- Narrower
Nolvadex
- Narrower
Tamoxifen Citrate
- Narrower
Tomaxithen
- Narrower
Zitazonium
- Narrower
ICI-46474
- Narrower
Soltamox
- Narrower
Concept UI |
M0021024 |
Scope note | One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. |
Preferred term | Tamoxifen |
Concept UI |
M0021027 |
Preferred term | ICI-47699 |
Entry term(s) |
ICI 47699 ICI47699 |
Concept UI |
M0373247 |
Preferred term | Nolvadex |
Entry term(s) |
Novaldex |
Concept UI |
M0373246 |
Preferred term | Tamoxifen Citrate |
Entry term(s) |
Citrate, Tamoxifen |
Concept UI |
M0021028 |
Preferred term | Tomaxithen |
Concept UI |
M0021025 |
Preferred term | Zitazonium |
Concept UI |
M0021026 |
Preferred term | ICI-46474 |
Entry term(s) |
ICI 46,474 ICI 46474 ICI-46,474 ICI46,474 ICI46474 |
Concept UI |
M0495698 |
Preferred term | Soltamox |
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