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Descriptor English: Testosterone
Descriptor Spanish: Testosterona
Descriptor testosterona
Scope note: Potente esteroide androgénico y principal producto de las CÉLULAS DE LEYDIG del TESTÍCULO. La HORMONA LUTEINIZANTE de la HIPÓFISIS estimula su producción. A su vez, la testosterona ejerce una autorregulación negativa de la secreción hipofisaria de hormona luteinizante (LH) y hormona estimulante del folículo (FSH). Además, dependiendo de los tejidos, la testosterona puede convertirse en DIHIDROTESTOSTERONA o ESTRADIOL.
Descriptor Portuguese: Testosterona
Descriptor French: Testostérone
Entry term(s): 17 beta Hydroxy 4 Androsten 3 one
17 beta Hydroxy 8 alpha 4 Androsten 3 one
17-beta-Hydroxy-4-Androsten-3-one
17-beta-Hydroxy-8 alpha-4-Androsten-3-one
8 Isotestosterone
8-Isotestosterone
AndroGel
Androderm
Andropatch
Androtop
Histerone
Sterotate
Sustanon
Testim
Testoderm
Testolin
Testopel
Testosterone Sulfate
Tree number(s): D04.210.500.054.079.429.824
D06.472.334.851.968.984
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013739
Scope note: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Annotation: TESTOSTERONE PROPIONATE is also available
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Androgens
Registry Number: 3XMK78S47O
CAS Type 1 Name: Androst-4-en-17beta-ol-3-one
Public MeSH Note: 1963; SUSTANON was indexed under TESTOSTERONE/AA 1976-2003; /therapeutic use was TESTOSTERONE, THERAPEUTIC 1965
History Note: 1963; for SUSTANON use TESTOSTERONE (NM) 1976-2003; /therapeutic use was TESTOSTERONE, THERAPEUTIC 1965
DeCS ID: 14118
Unique ID: D013739
NLM Classification: WJ 875
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Testosterone - Preferred
Concept UI M0021196
Scope note A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Preferred term Testosterone
Entry term(s) 17 beta Hydroxy 4 Androsten 3 one
17-beta-Hydroxy-4-Androsten-3-one
Androtop - Narrower
Concept UI M0476211
Preferred term Androtop
Histerone - Narrower
Concept UI M0476212
Preferred term Histerone
Sterotate - Narrower
Concept UI M0476213
Preferred term Sterotate
Sustanon - Narrower
Concept UI M0057170
Preferred term Sustanon
Androderm - Narrower
Concept UI M0476208
Preferred term Androderm
Testoderm - Narrower
Concept UI M0476219
Preferred term Testoderm
Testolin - Narrower
Concept UI M0476220
Preferred term Testolin
Testopel - Narrower
Concept UI M0476221
Preferred term Testopel
Testosterone Sulfate - Narrower
Concept UI M0021198
Preferred term Testosterone Sulfate
AndroGel - Narrower
Concept UI M0476209
Preferred term AndroGel
8-Isotestosterone - Related but not broader or narrower
Concept UI M0442765
Scope note Unlike testosterone, which is a flat molecule, its 8-isomer has a folded conformation.
Preferred term 8-Isotestosterone
Entry term(s) 17 beta Hydroxy 8 alpha 4 Androsten 3 one
17-beta-Hydroxy-8 alpha-4-Androsten-3-one
8 Isotestosterone
Andropatch - Narrower
Concept UI M0476210
Preferred term Andropatch
Testim - Narrower
Concept UI M0476218
Preferred term Testim



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