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Descriptor English:

Theophylline

Descriptor Spanish:

Teofilina

Spanish from Spain

Descriptor	teofilina
Scope note:	Metilxantina obtenida del té, con acción diurética, relajante del músculo liso, dilatador bronquial y estimulante cardíaco y del sistema nervioso central. La teofilina inhibe la NUCLEÓTIDO FOSFODIESTERASA 3',5'-CÍCLICA que degrada el AMP CÍCLICO, potenciando las acciones de los agentes que actúan mediante la ADENILIL CICLASA y el AMP cíclico.

Descriptor Portuguese:

Teofilina

Descriptor French:

Théophylline

Tree number(s):

D03.132.960.751
D03.633.100.759.758.824.751

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D013806

Scope note:

A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Bronchodilator Agents
Phosphodiesterase Inhibitors
Vasodilator Agents
Purinergic P1 Receptor Antagonists

Registry Number:

C137DTR5RG

CAS Type 1 Name:

1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-

DeCS ID:

14184

Unique ID:

D013806

NLM Classification:

QV 107