| Descriptor English: | 1-Methyl-3-isobutylxanthine | ||||||
| Descriptor Spanish: |
1-Metil-3-Isobutilxantina
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| Descriptor Portuguese: | 1-Metil-3-Isobutilxantina | ||||||
| Descriptor French: | Xanthine(isobutyl-3 methyl-1) | ||||||
| Entry term(s): |
1 Methyl 3 isobutylxanthine 3 Isobutyl 1 methylxanthine 3-Isobutyl-1-methylxanthine IBMX Isobutyltheophylline |
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| Tree number(s): |
D03.633.100.759.758.824.751.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015056 | ||||||
| Scope note: | A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Phosphodiesterase Inhibitors |
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| Registry Number: | TBT296U68M | ||||||
| CAS Type 1 Name: | 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)- | ||||||
| Previous Indexing: |
Phosphodiesterase Inhibitors (1978) Phosphodiesterases/antagonists & inhibitors (1972-1977) Xanthines (1966-1978) |
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| Public MeSH Note: | 91; was see under THEOPHYLLINE 1979-90 |
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| History Note: | 91(79); was see under THEOPHYLLINE 1979-90 |
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| Entry Version: | MIBX |
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| DeCS ID: | 8950 | ||||||
| Unique ID: | D015056 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1978/03/09 | ||||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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1-Methyl-3-isobutylxanthine
- Preferred
| Concept UI |
M0023168 |
| Scope note | A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES |
| Preferred term | 1-Methyl-3-isobutylxanthine |
| Entry term(s) |
1 Methyl 3 isobutylxanthine 3 Isobutyl 1 methylxanthine 3-Isobutyl-1-methylxanthine IBMX Isobutyltheophylline |
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