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Descriptor English: Thiamine Triphosphate
Descriptor Spanish: Tiamina Trifosfato
Descriptor trifosfato de tiamina
Scope note: 3-((4-amino-2-metil-5-pirimidinil)metil)-4-metil-5-(4,6,8,8-tetrahidroxi-3,5,7-trioxa-4,6,8-trifosfaoct-1-il)hidróxido de tiazolio, sal, P,P',P''-trióxido. El éster trifosfato de tiamina. En la enfermedad de Leigh, este compuesto se encuentra en cantidades reducidas en el cerebro, debido a un bloqueo metabólico en su proceso de formación.
Descriptor Portuguese: Tiamina Trifosfato
Descriptor French: Triphosphate de thiamine
Entry term(s): Thiamin Triphosphate
Triphosphate, Thiamin
Triphosphate, Thiamine
Tree number(s): D02.886.675.900.900
D03.383.129.708.900.900
D03.383.742.795.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013838
Scope note: 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
Annotation: do not confuse with THIAMIN TRIPHOSPHATASE; deficiency: coordinate THIAMINE TRIPHOSPHATE /defic (IM) with THIAMINE DEFICIENCY (IM)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Vitamin B Complex
Registry Number: 3475-65-8
CAS Type 1 Name: Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)-, inner salt, P,P',P''-trioxide
Previous Indexing: Organophosphorus Compounds (1971-1978)
Thiamine (1966-1978)
Public MeSH Note: 91; was see under THIAMINE 1979-90
History Note: 91(79); was see under THIAMINE 1979-90
DeCS ID: 14216
Unique ID: D013838
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/12/22
Revision Date: 2016/06/01
Thiamine Triphosphate - Preferred
Concept UI M0021326
Scope note 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
Preferred term Thiamine Triphosphate
Entry term(s) Thiamin Triphosphate
Triphosphate, Thiamin
Triphosphate, Thiamine



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