| Descriptor English: | Thiamine Pyrophosphate | ||||||
| Descriptor Spanish: | 
                                Tiamina Pirofosfato                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Tiamina Pirofosfato | ||||||
| Descriptor French: | Diphosphate de thiamine | ||||||
| Entry term(s): | 
                                    Berolase Cocarboxylase Pyrophosphate, Thiamine Thiamine Diphosphate  | 
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| Tree number(s): | 
                                        D02.886.675.900.702 D03.383.129.708.900.702 D03.383.742.795.702 D08.211.878  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013835 | ||||||
| Scope note: | The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. | 
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| Annotation: | do not confuse with THIAMINE PYROPHOSPHATASE; deficiency: coordinate THIAMINE PYROPHOSPHATE /defic (IM) with THIAMINE DEFICIENCY (IM) | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Vitamin B Complex | 
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| Registry Number: | Q57971654Y | ||||||
| CAS Type 1 Name: | Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride, P,P'-dioxide | ||||||
| DeCS ID: | 14213 | ||||||
| Unique ID: | D013835 | ||||||
| NLM Classification: | QU 135 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2016/06/01 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes 
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                        Thiamine Pyrophosphate                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Berolase                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0021323 | 
                                
| Scope note | The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. | 
| Preferred term | Thiamine Pyrophosphate | 
| Entry term(s) | 
                                        
                                                                                            Cocarboxylase                                                 Pyrophosphate, Thiamine Thiamine Diphosphate  | 
                                
| Concept UI | 
                                        
                                        M0373249 | 
                                
| Preferred term | Berolase | 
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