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Descriptor English: Thiouracil
Descriptor Spanish: Tiouracilo
Descriptor Portuguese: Tiouracila
Descriptor French: Thiouracile
Tree number(s): D03.383.742.698.875.842
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013889
Scope note: Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspected of terato- and carcinogenesis.
Annotation: a thyroid antag
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antithyroid Agents
Vasodilator Agents
Registry Number: 59X161SCYL
CAS Type 1 Name: 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-
DeCS ID: 14274
Unique ID: D013889
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/01
Thiouracil - Preferred
Concept UI M0021385
Scope note Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspected of terato- and carcinogenesis.
Preferred term Thiouracil



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