| Descriptor English: | Thromboxane-A Synthase | ||||||
| Descriptor Spanish: |
Tromboxano-A Sintasa
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| Descriptor Portuguese: | Tromboxano-A Sintase | ||||||
| Descriptor French: | Thromboxane-A synthase | ||||||
| Entry term(s): |
A2 Synthetase, Thromboxane Synthase, Thromboxane A Synthase, Thromboxane-A Synthetase, Thromboxane Synthetase, Thromboxane A2 Thromboxane A Synthase Thromboxane A2 Synthetase Thromboxane Synthetase |
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| Tree number(s): |
D08.811.399.475.900 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013930 | ||||||
| Scope note: | An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5. |
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| Annotation: | found in platelet microsomes |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 5.3.99.5 | ||||||
| CAS Type 1 Name: | (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase | ||||||
| Previous Indexing: |
Hydroxy Acids (1975-1977) Oxidoreductases (1966-1977) Pyrans (1966-1977) |
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| Public MeSH Note: | 98; see THROMBOXANE SYNTHETASE 1986-97; see OXIDOREDUCTASES 1978-85 |
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| History Note: | 98(78) |
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| DeCS ID: | 14316 | ||||||
| Unique ID: | D013930 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1986/01/01 | ||||||
| Date of Entry: | 1977/05/24 | ||||||
| Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Thromboxane-A Synthase
- Preferred
| Concept UI |
M0021440 |
| Scope note | An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5. |
| Preferred term | Thromboxane-A Synthase |
| Entry term(s) |
A2 Synthetase, Thromboxane Synthase, Thromboxane A Synthase, Thromboxane-A Synthetase, Thromboxane Synthetase, Thromboxane A2 Thromboxane A Synthase Thromboxane A2 Synthetase Thromboxane Synthetase |
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