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Descriptor English: Thymopoietins
Descriptor Spanish: Timopoyetinas
Descriptor timopoyetinas
Entry term(s) timinas
timopoyetina
timpoyetinas
Scope note: Dos polipéptidos estrechamente relacionados (peso molecular 7.000) aislados del timo. Estas hormonas inducen la diferenciación de los protimocitos para dar lugar a timocitos en el timo. También provocan un retraso de la trasmisión neuromuscular in vivo y por eso se piensa que pueden ser responsables de la miastenia grave.
Descriptor Portuguese: Timopoietinas
Descriptor French: Thymopoïétines
Entry term(s): TP 49
TP-49
Thymin
Thymins
Thymopoietin
Thymopoietin I
Thymopoietin II
Tree number(s): D06.472.910.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013946
Scope note: Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.
Annotation: do not confuse entry term THYMINS with THYMINE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Hormones (1966-1976)
Thymus Extracts (1974)
Thymus Gland (1966-1976)
Public MeSH Note: 91; was see under THYMUS HORMONES 1977-90
History Note: 91(77); was see under THYMUS HORMONES 1977-90
DeCS ID: 14334
Unique ID: D013946
NLM Classification: WK 400
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/19
Revision Date: 2020/05/27
Thymopoietins - Preferred
Concept UI M0021463
Scope note Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.
Preferred term Thymopoietins
Entry term(s) Thymin
Thymins
Thymopoietin
Thymopoietin I - Narrower
Concept UI M0021461
Preferred term Thymopoietin I
Thymopoietin II - Narrower
Concept UI M0021462
Preferred term Thymopoietin II
Entry term(s) TP 49
TP-49



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