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Descriptor English: Thymosin
Descriptor Spanish: Timosina
Descriptor timosina
Entry term(s) timosinas
Scope note: Familia de hormonas polipeptídicas termoestables que segrega el timo. Entre sus actividades biológicas se encuentran la linfocitopoyesis, la restauración de la competencia inmunitaria y el incremento de la expresión de las características y de la función de los linfocitos T. Se utilizan en el tratamiento de pacientes con inmunodeficiencias primarias o secundarias, cáncer o enfermedades relacionadas con el envejecimiento.
Descriptor Portuguese: Timosina
Descriptor French: Thymosine
Entry term(s): Thymosin Fs
Thymosins
Tree number(s): D06.472.910.850
D12.644.548.869
D12.776.922
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013947
Scope note: Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biological activities include lymphocytopoiesis, restoration of immunological competence and enhancement of expression of T-cell characteristics and function. They have therapeutic potential in patients having primary or secondary immunodeficiency diseases, cancer or diseases related to aging.
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 61512-21-8
CAS Type 1 Name: Thymosin
Previous Indexing: Glycoproteins (1973-1974)
Thymus Extracts (1974)
Thymus Gland (1973-1974)
Tissue Extracts (1973-1974)
Public MeSH Note: 84; was see under THYMUS HORMONES 1977-83, was see under THYMUS EXTRACTS 1975-76
History Note: 84(75); was see under THYMUS HORMONES 1977-83, was see under THYMUS EXTRACTS 1975-76
DeCS ID: 14335
Unique ID: D013947
NLM Classification: WK 400
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1974/11/19
Revision Date: 2006/07/05
Thymosin - Preferred
Concept UI M0021464
Scope note Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biological activities include lymphocytopoiesis, restoration of immunological competence and enhancement of expression of T-cell characteristics and function. They have therapeutic potential in patients having primary or secondary immunodeficiency diseases, cancer or diseases related to aging.
Preferred term Thymosin
Entry term(s) Thymosins
Thymosin Fs - Narrower
Concept UI M0021465
Preferred term Thymosin Fs



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