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Descriptor English: Thyroxine
Descriptor Spanish: Tiroxina
Descriptor tiroxina
Entry term(s) Berlthyrox
Dexnon
Eferox
Eltroxin
Eltroxine
Euthyrox
Eutirox
L Thyrox
L Tiroxina beta
L tiroxina
L tiroxina Roche
L-tiroxina
Levothroid
Levothyroid
Novotiral
Synthroid
T4
Unithroid
hormona tiroidea T4
levo T
levotiroxina
levotiroxina sódica
Scope note: Principal hormona producida por la glándula tiroides. Se forma por yodación de las tirosinas (MONOYODOTIROSINA) y el acoplamiento de las yodotirosinas (DIYODOTIROSINA) en la TIROGLOBULINA. La tiroxina se libera de la tiroglobulina mediante proteólisis y se secreta en la sangre. Periféricamente, la tiroxina pierde el yodo y se convierte en TRIYODOTIRONINA, que tiene una amplia gama de efectos estimulantes en el metabolismo celular.
Descriptor Portuguese: Tiroxina
Descriptor French: Thyroxine
Entry term(s): 3,5,3',5'-Tetraiodothyronine
Berlthyrox
Dexnon
Eferox
Eltroxin
Eltroxine
Euthyrox
Eutirox
L Thyrox
L Thyroxin Henning
L Thyroxin beta
L Thyroxine
L Thyroxine Roche
L-3,5,3',5'-Tetraiodothyronine
L-Thyrox
L-Thyroxin Henning
L-Thyroxin beta
L-Thyroxine
L-Thyroxine Roche
Levo T
Levo-T
Levothroid
Levothyroid
Levothyroxin Deladande
Levothyroxin Delalande
Levothyroxine
Levothyroxine Sodium
Levoxine
Levoxyl
Lévothyrox
Novothyral
Novothyrox
O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Oroxine
Sodium Levothyroxine
Synthroid
Synthrox
T4 Thyroid Hormone
Thevier
Thyrax
Thyroid Hormone, T4
Thyroxin
Tiroidine
Tiroxina Leo
Unithroid
Tree number(s): D06.472.931.812
D12.125.072.050.767
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013974
Scope note: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Annotation: /blood: consider also HYPERTHYROXINEMIA
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: Q51BO43MG4
CAS Type 1 Name: Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
Public MeSH Note: 1965; see THYROXIN 1963-1964; for LEVOTHYROXINE see LEVOTHYROXINE 1991-2001, see THYROXINE 1966-1990, see LEVOTHYROXINE 1963-1965
History Note: 1965; use THYROXIN 1963-1964; for LEVOTHYROXINE use LEVOTHYROXINE 1991-2001, use THYROXINE 1966-1990
Related: Hyperthyroxinemia MeSH
Receptors, Thyroid Hormone MeSH
DeCS ID: 14360
Unique ID: D013974
NLM Classification: WK 202
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/02/28
Thyroxine - Preferred
Concept UI M0021504
Scope note The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Preferred term Thyroxine
Entry term(s) 3,5,3',5'-Tetraiodothyronine
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
T4 Thyroid Hormone
Thyroid Hormone, T4
Thyroxin
Synthrox - Narrower
Concept UI M0463516
Preferred term Synthrox
Levothyroxine Sodium - Narrower
Concept UI M0373450
Preferred term Levothyroxine Sodium
Entry term(s) Sodium Levothyroxine
Thyrax - Narrower
Concept UI M0463511
Preferred term Thyrax
Tiroidine - Narrower
Concept UI M0463517
Preferred term Tiroidine
Tiroxina Leo - Narrower
Concept UI M0463518
Preferred term Tiroxina Leo
Unithroid - Narrower
Concept UI M0463519
Preferred term Unithroid
Eferox - Narrower
Concept UI M0463499
Preferred term Eferox
Eltroxin - Narrower
Concept UI M0463500
Preferred term Eltroxin
Entry term(s) Thevier
Eltroxine - Narrower
Concept UI M0024800
Preferred term Eltroxine
Euthyrox - Narrower
Concept UI M0463502
Preferred term Euthyrox
Entry term(s) Eutirox
L-Thyrox - Narrower
Concept UI M0463506
Preferred term L-Thyrox
Entry term(s) L Thyrox
L-Thyroxin beta - Narrower
Concept UI M0463503
Preferred term L-Thyroxin beta
Entry term(s) L Thyroxin beta
L-Thyroxin Henning - Narrower
Concept UI M0463504
Preferred term L-Thyroxin Henning
Entry term(s) L Thyroxin Henning
Levothyroxine - Narrower
Concept UI M000640387
Preferred term Levothyroxine
Entry term(s) L Thyroxine
L-3,5,3',5'-Tetraiodothyronine
L-Thyroxine
O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
Levoxine - Narrower
Concept UI M0373451
Preferred term Levoxine
Levoxyl - Narrower
Concept UI M0378850
Preferred term Levoxyl
Lévothyrox - Narrower
Concept UI M0463512
Preferred term Lévothyrox
L-Thyroxine Roche - Narrower
Concept UI M0463505
Preferred term L-Thyroxine Roche
Entry term(s) L Thyroxine Roche
Levo-T - Narrower
Concept UI M0463507
Preferred term Levo-T
Entry term(s) Levo T
Levothroid - Narrower
Concept UI M0463508
Preferred term Levothroid
Novothyral - Narrower
Concept UI M0070173
Preferred term Novothyral
Berlthyrox - Narrower
Concept UI M0463497
Preferred term Berlthyrox
Dexnon - Narrower
Concept UI M0463498
Preferred term Dexnon
Novothyrox - Narrower
Concept UI M0463513
Preferred term Novothyrox
Oroxine - Narrower
Concept UI M0463515
Preferred term Oroxine
Synthroid - Narrower
Concept UI M0373452
Preferred term Synthroid
Levothyroxin Deladande - Narrower
Concept UI M0463509
Preferred term Levothyroxin Deladande
Entry term(s) Levothyroxin Delalande
Levothyroid - Narrower
Concept UI M0373368
Preferred term Levothyroid



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