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Descriptor English: Tretinoin
Descriptor Spanish: Tretinoina
Descriptor tretinoina
Entry term(s) ácido all-trans-retinoico
ácido de vitamina A
ácido retinoico
ácido retinoico all trans
ácido retinoico all-trans
ácido retinoico todo trans
ácido retinoico todo-trans
ácido todo-trans-retinoico
Scope note: Importante regulador de la EXPRESIÓN GÉNICA durante el crecimiento y desarrollo y en NEOPLASIAS. La tretinoína, también conocida como ácido retinoico y derivado de la VITAMINA A materna, es esencial para el CRECIMIENTO normal y el DESARROLLO EMBRIONARIO. Un exceso de tretinoína puede ser teratogénico. Se utiliza en el tratamiento de la PSORIASIS, ACNÉ VULGAR y otras ENFERMEDADES DE LA PIEL. También se ha aprobado para su empleo en la leucemia promielocítica (LEUCEMIA PROMIELOCÍTICA AGUDA).
Descriptor Portuguese: Tretinoína
Descriptor French: Trétinoïne
Entry term(s): Acid, Retinoic
Acid, Vitamin A
Acid, all-trans-Retinoic
Acid, beta-all-trans-Retinoic
Acid, trans-Retinoic
Potassium Salt, Tretinoin
Retin A
Retin-A
Retinoic Acid
Salt, Tretinoin Potassium
Salt, Tretinoin Sodium
Salt, Tretinoin Zinc
Sodium Salt, Tretinoin
Tretinoin Potassium Salt
Tretinoin Sodium Salt
Tretinoin Zinc Salt
Vesanoid
Vitamin A Acid
Zinc Salt, Tretinoin
all trans Retinoic Acid
all-trans-Retinoic Acid
beta all trans Retinoic Acid
beta-all-trans-Retinoic Acid
trans Retinoic Acid
trans-Retinoic Acid
Tree number(s): D02.455.326.271.665.202.495.818.500
D02.455.426.392.368.367.379.249.700.860.500
D02.455.849.131.495.818.800
D02.455.849.291.925.500
D23.767.261.700.780
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014212
Scope note: An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Keratolytic Agents
Registry Number: 5688UTC01R
CAS Type 1 Name: Retinoic acid
Previous Indexing: Carotenoids (1969-1974)
Vitamin A (1966-1974)
Public MeSH Note: 80; was see under VITAMIN A 1975-79
History Note: 80(75); was see under VITAMIN A 1975-79
Related: Receptors, Retinoic Acid MeSH
DeCS ID: 14606
Unique ID: D014212
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2013/07/08
Tretinoin - Preferred
Concept UI M0021879
Scope note An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
Preferred term Tretinoin
Entry term(s) Acid, Retinoic
Acid, Vitamin A
Acid, all-trans-Retinoic
Acid, trans-Retinoic
Retinoic Acid
Vitamin A Acid
all trans Retinoic Acid
all-trans-Retinoic Acid
trans Retinoic Acid
trans-Retinoic Acid
Retin-A - Related but not broader or narrower
Concept UI M0021881
Preferred term Retin-A
Entry term(s) Retin A
Tretinoin Potassium Salt - Narrower
Concept UI M0329549
Preferred term Tretinoin Potassium Salt
Entry term(s) Potassium Salt, Tretinoin
Salt, Tretinoin Potassium
Tretinoin Zinc Salt - Narrower
Concept UI M0329550
Preferred term Tretinoin Zinc Salt
Entry term(s) Salt, Tretinoin Zinc
Zinc Salt, Tretinoin
Vesanoid - Related but not broader or narrower
Concept UI M0021882
Preferred term Vesanoid
beta-all-trans-Retinoic Acid - Narrower
Concept UI M0021880
Preferred term beta-all-trans-Retinoic Acid
Entry term(s) Acid, beta-all-trans-Retinoic
beta all trans Retinoic Acid
Tretinoin Sodium Salt - Narrower
Concept UI M0329548
Preferred term Tretinoin Sodium Salt
Entry term(s) Salt, Tretinoin Sodium
Sodium Salt, Tretinoin



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