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Descriptor English: Valinomycin
Descriptor Spanish: Valinomicina
Descriptor valinomicina
Scope note: Antibiótico ionóforo ciclododecadepsipéptido producido por Streptomyces fulvissimus y relacionado con las eniatinas. Está constituido por 3 moles de cada uno de los siguientes compuestos: L-valina, ácido D-alfa-hidroxisovalérico, D-valina y ácido L-láctico. Estos se enlazan alternadamente para formar un anillo de 36 miembros. (Merck Index, 11th ed) La valinomicina es un ionóforo selectivo de potasio y se usa frecuentemente como herramienta en los estudios bioquímicos.
Descriptor Portuguese: Valinomicina
Descriptor French: Valinomycine
Tree number(s): D04.345.566.297.500
D12.644.641.297.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014634
Scope note: A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Ionophores
Registry Number: 2001-95-8
CAS Type 1 Name: Valinomycin
Previous Indexing: Antibiotics (1966-1970)
Public MeSH Note: 73
History Note: 73(71)
DeCS ID: 15038
Unique ID: D014634
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Valinomycin - Preferred
Concept UI M0022498
Scope note A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
Preferred term Valinomycin



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